Sepsis
Conditions
Interventions
Sham-TEA group:traditional treatment and Sham-TEA treatment
TEA group:traditional treatment and TEA treatment
Healthy control group:none
Sponsors
Jiangnan University Medical Center (Wuxi No.2 People’s Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.conform to the diagnosis criteria of sepsis as proposed in the Third International Consensus Definitions for Sepsis and Septic Shock(Sepsis-3) in 2016; 2. conform to the diagnostic criteria of the Acute Gastrointestinal Injury (AGI) classification proposed by the European Society of Intensive Care Medicine in 2012, Acute Gastrointestinal Injury (AGI) grade I-IV; 3. Age :18-80 years ; 4. The patient or their family members sign a written consent form.
Exclusion criteria
Exclusion criteria: 1.taking medicines or food affecting GI motility within the last 2 weeks; 2.history of digestive surgery (except appendectomy and cholecystectomy); 3. Diseases leading to GI dysmotility including chronic constipation, etc.; 4. women prepare for pregnancy or during pregnancy; 5.allergy to skin preparation or electrodes; 6. Those who have a recent history of acupuncture and moxibustion, physiotherapy and other traditional Chinese medicine therapies or are familiar with traditional Chinese medicine therapies;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Symptom score (abdominal pain, bloating, nausea, vomiting, anorexia); | — |
Secondary
| Measure | Time frame |
|---|---|
| APACHE ?;acute gastrointestinal injury, AGI;The time to first defecation, the time to first flatus;ICU hospital day;28 day mortality rate;electrogastrogram, EGG;heart rate variability, HRV;Blood routine;renal function;interleukin-10,IL-10;TNF-a;interleukin-1ß,IL-1ß;Gastric emptying detection by ultrasound;interleukin 6,IL-6;lactic acid;albumin; | — |
Countries
China
Contacts
Public ContactWu Gao-jue
Jiangnan University Medical Center (Wuxi No.2 People’s Hospital (North branch) )
Outcome results
None listed