Schizophrenia/Major Depression Disorder
Conditions
Interventions
Subclinical depression group1:fNRIS neurofeedback intervention targeting dmPFC
Schizophrenia group1:fNRIS neurofeedback intervention targeting dmPFC
Schizophrenia group2:fNRIS neurofeedback intervention targeting dlPFC
Schizophrenia group3:fNRIS neurofeedback intervention targeting vlPFC
Schizophrenia group4:fNRIS neurofeedback intervention targeting mOFC
Schizophrenia group5:sham intervention
MDD group1:fNRIS neurofeedback intervention targeting dmPFC
MDD group2:fNRIS neurofeedback intervention targeting dlPFC
MDD group3:fNRIS neurofeedback intervention targeting vlPFC
MDD group4:fNRIS neurofeedback intervention targeting mOFC
MDD group5:sham intervention
Subclinical depression group2:fNRIS neurofeedback intervention targeting dlPFC
Subclinical depression group3:fNRIS neurofeedback intervention targeting vlPFC
Subclinical depression group4: fNRIS neurofeedback intervention targeting mOFC
Subclinical depression group5:sham intervention
Social anhedonia group1:fNRIS neurofeedback intervention targeting dmPFC
Social anhedonia group2:fNRIS neurofeedback intervention targeting dlPFC
Social anhedonia group3:fNRIS neurofeedback intervention targeting vlPFC
Social anhedonia group4:fNRIS neurofeedback intervention targeting mOFC
Social anhedonia group5:sham intervention
Sponsors
School of Psychology and Cognitive Science, East China Normal University
Eligibility
Sex/Gender
All
Age
12 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Inclusion criteria for patients with depressive episode: (1) Meet the DSM-V diagnostic criteria for depressive episodes; (2) 12-50 years old; (3) IQ above 70; (4) The course of disease is less than 5 years; (5) The disease was controlled by drugs and was not in the onset period. 2. Inclusion criteria for patients with schizophrenia: (1) Meet the DSM-V diagnostic criteria for schizophrenia; (2) IQ greater than 70; (3) patients aged 12-18 years or patients under 50 years of age with early-onset schizophrenia; (4) right-handed; (5) The disease was controlled by drugs and was not in the onset period. 3. Inclusion criteria for subclinical depression patients (1) Individuals with BDI scale scores higher than 16; (2) 12-50 years old; (3) IQ above 70. 4. Inclusion criteria of patients in social anhedonia group: (1) Individuals with scores higher than 20 on CSAS scale; (2) 12-50 years old; (3) IQ above 70.
Exclusion criteria
Exclusion criteria: 1. Exclusion criteria for patients with depressive episode: (1) Non-convulsive electroconvulsive therapy (MECT) was used within 8 weeks; (2) Antipsychotics were significantly adjusted within 8 weeks; (3) perinatal trauma; (4) substance and/or alcohol abuse; (5) the combination of other axis a mental illness; (6) History of local brain injury or neurological disease 2. Exclusion criteria for patients with schizophrenia: (1) Non-convulsive electroconvulsive therapy within 8 weeks; (2) Antipsychotic drug adjustment within 8 weeks; (3) Substance/alcohol abuse; (4) Mental illness associated with other axis 1; (5) History of local brain injury/neurological disease; (6) claustrophobia; (7) Metal implantation in vivo. 3. Exclusion criteria for subclinical depression group: (1) All mental disorders or personality disorders diagnosed by the DSM-V; (2) perinatal trauma; (3) substance and/or alcohol abuse; (4) History of local brain injury or neurological disease. 4. Exclusion criteria for social anhedonia group: (1) All mental disorders or personality disorders diagnosed by the DSM-V; (2) perinatal trauma; (3) substance and/or alcohol abuse; (4) History of local brain injury or neurological disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical evaluation;Behavioral task;Magnetic Resonance Imaging;Scale scores;Blood oxygen signal based on fNIRS; | — |
Countries
China
Contacts
Public ContactYan Chao
School of Psychology and Cognitive Science, East China Normal University
Outcome results
None listed