The Application of Platelet-Rich Plasma (PRP) in the Surgical Treatment of Osteochondral Lesions of the Talus

The Application of Platelet-Rich Plasma in the Surgical Treatment of Osteochondral Lesions of the Talus

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400086095

Enrollment

Unknown

Registered

2024-06-25

Start date

2023-12-18

Completion date

Unknown

Last updated

2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteochondral Lesions of the Talus

Interventions

Experimental group:After filling the defect with cancellous bone, it will be covered with PRP gel.

Control group:After filling the defect with cancellous bone, it will be covered with Fibrin gel.

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Patients aged 18 to 60 with osteochondral lesions of the talus (Hepple type V) or those who have failed conservative treatment or bone marrow stimulation therapy.

Exclusion criteria

Exclusion criteria: Coagulation disorders; severe osteoporosis; patients with tumors; patients with ankle joint infections; previous surgical history affecting ankle joint mobility; poor compliance.

Design outcomes

Primary

Measure	Time frame
Visual Analogue scale (VAS) score;American Orthopaedic Foot and Ankle Society (AOFAS) score;Foot and Ankle Outcome Score (FAOS);	—

Secondary

Measure	Time frame
Imaging findings (MRI, CT);Intraoperative findings, postoperative complications, etc.;	—

Countries

China

Contacts

Public ContactQi Li

West China Hospital of Sichuan University

liqi_sports@scu.edu.cn+86 189 8060 6998

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026