thoracic surgery
Conditions
Interventions
Drive a pressure-oriented positive end-expiratory pressure group:The personalized PEEP strategy was used, that is, on the basis of the initial PEEP of 0cmH2O, the PEEP was gradually increased until th
Control Group:PEEP is set to fixed 5cm H2O
Sponsors
Weihai Municipal Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: ? Patients aged 18-65 years of age who intend to undergo unilateral lobectomy/segmental resection, regardless of thoracotomy or thoracoscopic surgery. ? ASA grade I-III, BMI 18-26kg/m2. ? There were no serious respiratory abnormalities in preoperative pulmonary function. ? no cold, pneumonia and so on within 1 month before surgery. ? No previous lung surgery or other major surgery.
Exclusion criteria
Exclusion criteria: ? Combined with grade 3 hypertension, poorly controlled diabetes, central nervous system disease, severe arrhythmia, etc ? Serious illness may affect research results. ? Allergy or suspected allergy to the investigational drug. ? The patient has participated in clinical studies of other drugs or devices within 6 months. There are contraindications for double-chamber tracheal intubation. ? Serious preoperative pulmonary dysfunction or preoperative blood gas analysis suggested respiratory failure. ? Preoperative CT suggested lung infection, atelectasis, pleural effusion and other abnormalities.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative pulmonary complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intraoperative respiratory parameters;Arterial blood gas;blood test; | — |
Countries
China
Contacts
Public ContactWang Xiaodong
Weihai Municiple Hospital
Outcome results
None listed