carcinoma of the lungs
Conditions
Interventions
Dex group:Start administering 1 µg/kg of dexmedetomidine 30 minutes before anesthesia induction, diluted in 5 ml and delivered via inhalation for 10 minutes.
Control group:Start administering 5 ml of normal saline via inhalation 30 minutes before anesthesia induction.
Sponsors
Henan Provincial People's Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) Female patients scheduled for thoracoscopic lung cancer resection. 2) Anesthesia administered via intravenous general anesthesia. 3) Surgery duration exceeding 1 hour. 4) Age range between 18 and 65 years. 5) ASA classification levels I-III. 6) Voluntary signing of informed consent.
Exclusion criteria
Exclusion criteria: 1) Patients undergoing perioperative radiotherapy or chemotherapy. 2) Individuals with severe cardiovascular or cerebrovascular diseases. 3) Patients with severe liver or kidney dysfunction. 4) Those with comorbid psychiatric illnesses. 5) Patients with changes in the surgical approach. 6) Postoperative transfer to the intensive care unit.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative nausea and vomiting; | — |
Secondary
| Measure | Time frame |
|---|---|
| QOR Recovery Quality Rating Scale;VAS pain score;Sleep score;Anxiety and depression scale;PCIA press;Dose and time of remedy analgesic and antiemetic drugs;postoperative sore throat score;Postoperative adverse reactions such as hypertension, hypotension, bradycardia, respiratory depression and dizziness within 48 hours after operation; | — |
Countries
China
Contacts
Public ContactZhang Wei
Henan Provincial People's Hospital
Outcome results
None listed