A prospective randomized controlled study of high-dose estrogen in preventing adhesion recurrence after hysteroscopic adhesiolysis

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2400086064

Enrollment

Unknown

Registered

2024-06-14

Start date

2024-07-01

Completion date

Unknown

Last updated

2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intrauterine adhesion

Interventions

no estrogen group:no estrogen therapy after intrauetrine adhesiolysis

high-dose estrogen group:8mg/d estrogen therapy after intrauetrine adhesiolysis

Eligibility

Sex/Gender

Female

Age

20 Years to 40 Years

Inclusion criteria

Inclusion criteria: women aged 18–40 years; written consent obtained; moderate and severe IUA(AFS score 5-12)and agreement to have second-look hysteroscopy.

Exclusion criteria

Exclusion criteria: Age > 40 years or < 20 years;Patients with mild intrauterine adhesion;istory of uterine artery embolization;Or genital tuberculosis history;History of endometrial lesions;History of thrombosis; Hormone replacement therapy within 3 months;Patients with severe internal complications; Pregnancy status;Fever or infection before operation;Malignant tumor;History of pelvic inflammatory disease;Patients with contraindications to anesthesia;Those who do not understand or approve the randomized controlled trial.

Design outcomes

Primary

Measure	Time frame
Incidence of adhesion reformation;AFS score;mestrual improvement;	—

Secondary

Measure	Time frame
pregnant outcome;	—

Countries

China

Contacts

Public ContactLiulinlin

Hysteroscopy center,Capital Medical University affiliated Fuxing Hospital

wslinlin26@hotmail.com+86 150 0128 4276

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026