persistent atrial fibrillation
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Age range from 18 to 80 years old; (2) Persistent atrial fibrillation confirmed by dynamic electrocardiogram; (3) Voluntarily accept the first radiofrequency ablation treatment and sign the surgical consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with paroxysmal atrial fibrillation; (2) Severe organic heart disease (severe mitral regurgitation, dilated cardiomyopathy, hypertrophic cardiomyopathy, and other severe valvular disease); (3) After combining congenital heart disease or patent foramen ovale and performing occlusion or surgical repair surgery; (4) After artificial valve implantation surgery; (5) Contraindications to systemic anticoagulation; (6) A history of stroke for any reason within 3 months; (7) Have a history of bleeding in the past 30 days or a high risk of bleeding in the past; (8) Platelet count3 x upper limit of maximum limit (ULN); (13) Life expectancy is less than 1 year; (14) Previously implanted any type of pacemaker or after left atrial appendage occlusion surgery; (15) Acute myocardial infarction or PCI within 3 months, with a history of CABG within 6 months; (16) After catheter ablation for previous arrhythmias (including atrial fibrillation); (17) The anterior posterior diameter of the left atrium measured along the long axis of the sternum is = 60mm; (18) Left ventricular ejection fraction<40% or in the decompensated phase of heart failure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of free of atrial arrhythmias such as atrial fibrillation, atrial flutter, or atrial tachycardia for more than 30 seconds within 1 year after operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| The total procedure time under DC-EPS AF ablation strategy;The fluoroscopy time under DC-EPS AF ablation strategy;Radiofrequency ablation time under DC-EPS AF ablation strategy; | — |
Countries
China
Contacts
Sun Yat-sen Memorial Hospital of Sun Yat-sen University