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A multi-omics-based study of the dynamic evolution of atherosclerotic cardiovascular disease and related mechanisms

Study on the associations and mechanisms between omics and severity of atherosclerotic cardiovascular disease

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400086022
Enrollment
Unknown
Registered
2024-06-24
Start date
2024-10-01
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

corony heart disease

Interventions

acute myocardial infarction (AMI):no interventions
Unstable angina (UA):no interventions
chronic coronary syndrome (CCS):no interventions
Normal Coronary Artery (NCA):no interventions

Sponsors

The First Affiliated Hospital of Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 1. aged more than 18 years 2. Meets diagnostic criteria for coronary atherosclerosis 3. undergo coronary angiography after admission 4. able to sign the informed consent form

Exclusion criteria

Exclusion criteria: Exclusion criteria: 1. severe valvular disease (defined as valvular disease stage C or D) 2. hypertrophic cardiomyopathy; pulmonary heart disease 2) gastrointestinal disease 3. hyperthyroidism, anemia, or any other high-intensity heart disease 4. malignant tumors 5. severe dysfunction of the liver (defined as alanine aminotransferase or total bilirubin greater than 3 times the upper limit of normal) or kidney (defined as eGFR) >20 mL/min/1.73m2 or requiring dialysis) 6. severe congenital heart disease 7. severe infectious or contagious disease 8. autoimmune disease 9. patients with incomplete clinical records

Design outcomes

Primary

MeasureTime frame
All-cause mortality (ACM);

Secondary

MeasureTime frame
Major adverse cardiovascular events (MACE);

Countries

China

Contacts

Public ContactJunnan Tang

The First Affiliated Hospital of Zhengzhou University

fcctangjn@zzu.edu.cn+86 158 9069 6166

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026