gastric endoscopic submucosal dissection-induced ulcer
Conditions
Interventions
Treatment group:Vonorasan + aluminium phosphate gel
Control group:Esomeprazole + aluminium phosphate gel
Sponsors
Affiliated Hospital of Guangdong Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Meets surgical indications for ESD; 2. Age 18-70 years, regardless of gender; 3. Normal coagulation; 4. ESD Postoperative ulcers =3cm; 5. Voluntary participation in the study.
Exclusion criteria
Exclusion criteria: 1. Patients with severe complications or failure to achieve curative resection after gastric ESD surgery need supplementary surgery; 2. Women who are pregnant or breastfeeding, or who may conceive during clinical trials; 3. The patient has other serious organic diseases that affect the evaluation of the study, such as severe liver disease, heart disease, renal disease, malignant neoplasm and alcoholism; 4. Patients who need to take antiplatelet and NSAIDS drugs for a long period of time; 5. Co-administration of unspecified anti-ulcer drugs during the trial period; 6. Allergic reactions to vornoxan, aluminium phosphate gel or esomeprazole; 7. Patients with no capacity for autonomous behaviors, unable to correctly express their main complaint, such as those with mental illness, severe neurosis, and unable to cooperate with this experiment 8. ESD Postoperative ulcers >3cm.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of ulcer reduction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Size of ulcer;Rate of ulcer healing;Incidence of wart-like projections;Quality of ulcer healing;Incidence of delayed hemorrhage;Postoperative symptom relief rate; | — |
Countries
China
Contacts
Public ContactYe Shicai /Yang Yuping
Affiliated Hospital of Guangdong Medical University
Outcome results
None listed