allergic rhinitis
Conditions
Interventions
Health group:Healthy children do not need intervention.
AR with constipation group:Children with constipation were given one bag of Kupei dietary fiber per time, twice a day, with a 3-day pause in case of diarrhea. Starting from the first week, add one bag
Sponsors
Longgang District Maternity & Child Healthcare Hospital,Shenzhen
Eligibility
Sex/Gender
All
Age
3 Years to 7 Years
Inclusion criteria
Inclusion criteria: ? Age = 3 years old, = 7 years old; ? Meet the diagnostic criteria for allergic rhinitis; ? Functional constipation is present.
Exclusion criteria
Exclusion criteria: ? Chronic digestive system diseases: such as Inflammatory bowel disease, Ulcerative colitis, etc. ? Structural diseases such as Colorectal polyp and colon cancer. ? Congenital digestive system structural abnormalities such as hirschsprung's disease. ? Routine drug intervention: including intestinal motility drugs, anticholinergics, rifampicin and other drugs to treat constipation. In addition, there are also those who have used antibiotics and probiotics within 4 weeks before enrollment. ? Diabetes, hypothyroidism, Hyperthyroidism and other Endocrine system diseases. ? Uremia, severe liver disease, renal insufficiency and other serious diseases. ? Gallbladder system diseases such as Cholecystitis and Gallstone. ? Severe mental illness, such as depression, psychological disorders, etc. ? History of surgery, trauma, and serious illness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The abundance of gut microbiota ;The level of metabolites in serum;The concentration of gut microbiota metabolites; | — |
Countries
China
Contacts
Public ContactHuang Congfu
Longgang District Maternity & Child Healthcare Hospital,Shenzhen
Outcome results
None listed