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Study on the mechanism of frontal lobe network regulated by vagus magnetic stimulation to promote the recovery of cognitive and upper limb motor dysfunction after ischemic stroke

Study on the mechanism of frontal lobe network regulated by vagus magnetic stimulation to promote the recovery of cognitive and upper limb motor dysfunction after ischemic stroke

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400085969
Enrollment
Unknown
Registered
2024-06-21
Start date
2024-07-01
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cognitive combined with upper limb motor dysfunction after ischemic stroke

Interventions

VNM group:Vagus Nerve Magnetic Stimulation

Sponsors

The First Affiliated Hospital of Fujian Medical University, Fujian
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age 40-80 years old; 2. Montreal Cognitive Function Assessment Scale (MoCA) score =26 points; 3.Duration less than half a year ;4. Subject agrees to accept the study by signing informed consent prior to study;5.Patients who can tolerate neuroregulatory tests.

Exclusion criteria

Exclusion criteria: ? Unstable vital signs; ? Intracranial malignant tumors or unruptured aneurysms; ? History of seizures or cerebral accumulation water; ? disturbance of consciousness and severe cognitive impairment; (5) Intracranial metal implantation or installation of cardiac pacemakers; ? Severe cardiovascular and liver and kidney function capable of disease; ? can not cooperate with inspection; History of cognitive impairment and motor dysfunction of the affected upper limb; ? Other peripheral magnetic stimulation treatment contraindications.

Design outcomes

Primary

MeasureTime frame
functional near-infrared spectroscopy;Upper Limb Fugl-Meyer Assessment;Mini-mental State Examination,MMSE;motor evoked potential, MEP;Wolf Motor Function Test,WMFT;

Secondary

MeasureTime frame
Event-related potential P300;Functional Independence Measure,FIM;

Countries

China

Contacts

Public ContactXia-Hua Liu

The First Affiliated Hospital of Fujian Medical University, Fujian

1014256630@qq.com+86 158 0603 8892

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026