abdominal operation
Conditions
Interventions
experiment group:The PEEP level corresponding to the minimum mechanical power identified through PEEP titration screening and recruitment maneuvers
control group:Volume-controlled ventilation mode with a fixed PEEP of 5cmH2O
Sponsors
The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
60 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.Age 60-85 years old; 2.ASA class I-III; 3.BMI between 18kg/m2 and 30kg/m2; 4.Scheduled for abdominal surgery; 5.The operation lasted more than two hours; 6.Informed and willing to participate in the trial, and willing to sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1.Severe pulmonary diseases such as chronic obstructive pulmonary disease, pleural effusion, pneumothorax, and bullous lung disease; 2.Severe cardiac, hepatic, renal, or hematologic disorders; 3.Central nervous system disorders impairing respiratory function; 4.Contraindications for PEEP use: intracranial hypertension, bronchopleural fistula, hypovolemic shock, etc.; 5.Participation in other clinical studies within the last 3 months; 6.Patients who refuse to participate in the trial or cannot cooperate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pulmonary complications;the seveity grade of postoperative pulmonary complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| during hospitalization after surgery;Ventilator parameters;Arterial blood gas;Oxygenation index;Mechanical power;Driving pressure;Dynamic lung compliance;Lung static compliance;lung ultrasound;Ultrasound diaphragmatic function; | — |
Countries
China
Contacts
Public ContactChen Lijian
The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed