brain disorder
Conditions
Interventions
Cases group:Defined as the occurrence of brain dysfunction based on follow-up results
Sponsors
The First Hospital Affiliated to the University of Science and Technology of China
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Patients requiring elective surgery under general anesthesia, older than 18 years of age, with cardiac function class I-III
Exclusion criteria
Exclusion criteria: 1) patients with poor cardiac function (EF 50% or significant differences in hemodynamic indexes of the right and left carotid arteries; 3) preoperative neurological disorders such as cerebral embolism, cerebral hemorrhage, motor, sensory, cognitive disorders due to non-neurogenic factors, or the use of medications acting on the central nervous system; 4) serious systemic diseases such as liver and renal insufficiency before surgery; preoperative Montreal Cognitive Assessment Scale (MoCA) score <26 points; 4) serious systemic diseases such as liver and renal insufficiency; 4) patients who had the following conditions central nervous system; preoperative Montreal Cognitive Assessment (MoCA) score <26; 4) preoperative serious systemic diseases such as liver and renal insufficiency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| carotid blood flow;peak systolic velocity; end systolic velocity;pulsatility index;resistive index;Jugular arteriovenous oxygen saturation;a-vDO2; | — |
Secondary
| Measure | Time frame |
|---|---|
| Stroke Volume Variability;Systemic Vascular Resistance;Cardiac Index;Corrected flow time;Carotid artery velocity time integral; | — |
Countries
China
Contacts
Public ContactYanhuXie
The First Hospital Affiliated to the University of Science and Technology of China
Outcome results
None listed