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Exploring the efficacy of dual-target rTMS therapy in the cerebellum combined with the M1 region of the brain on upper limb dyskinesia after stroke

Exploring the efficacy of dual-target rTMS therapy in the cerebellum combined with the M1 region of the brain on upper limb dyskinesia after stroke - Exploring the efficacy of dual-target rTMS therapy in the cerebellum combined with the M1 region of the brain on upper limb dyskinesia after stroke

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400085933
Enrollment
Unknown
Registered
2024-06-21
Start date
2024-06-21
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke upper limb dyskinesia

Interventions

G1:The rTMS sham stimulation was given on the basis of conventional rehabilitation treatment, first to the cerebellar hemisphere contralateral to the lesion and then immediately to the M1 area of the
G2:The rTMS treatment was given on the basis of the conventional rehabilitation treatment. rTMS was first used to stimulate the contralateral cerebellar hemisphere of the lesion, followed immediately
G3:The rTMS treatment was given on the basis of the conventional rehabilitation treatment. rTMS was first used for sham stimulation of the cerebellar hemisphere on the contralateral side of the lesion
G4:The rTMS treatment was given on the basis of conventional rehabilitation therapy. rTMS was first used to stimulate the contralateral cerebellar hemisphere of the lesion, followed immediately by sti

Sponsors

The First Affiliated Hospital of Gannan Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: (1) Age =18 years, gender is not limited; (2) Patients with first onset of cerebral hemorrhage or cerebral infarction in one cerebral hemisphere confirmed by CT/MRI; (3) Time of onset > 2 weeks, with stable vital signs; (4) Patients with unilateral upper limb dysfunction and Fulg-Meyer upper limb score <60; (5) The patients or their immediate family members were able and willing to sign the informed consent.

Exclusion criteria

Exclusion criteria: (1) Patients with severe cardiac, pulmonary, hepatic and renal insufficiency; (2) Upper limb dysfunction secondary to other diseases; (3) Patients with a history of epilepsy; (4) Contraindications to transcranial magnetic therapy such as cranial defects or intracranial metal built-in objects, high intracranial pressure and so on; (5) Pregnant or lactating women; (6) Those who are participating in other clinical studies or have participated in other clinical studies within 3 months before admission; (7) Patients with poor compliance and inability to cooperate with evaluation and treatment; (8) Other patients deemed by the investigator to be unsuitable for enrollment.

Design outcomes

Primary

MeasureTime frame
Fugl-Meyer Assessment-Upper Extremity;

Secondary

MeasureTime frame
modified Ashworth scale;Modified Barthel Index;Functional near infra-red spectroscopy;

Countries

China

Contacts

Public ContactYun Luo

Department of Rehabilitation, The First Affiliated Hospital of Gannan Medical University, Ganzhou City, Jiangxi Province, China

735083566@qq.com+86 157 5430 6145

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026