vascular cognitive impairment
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: ? The diagnosis was consistent with the diagnostic criteria of vascular cognitive impairment in Tian Jinzhou's "Chinese Guidelines for the Diagnosis of Vascular Mild Cognitive Impairment" in 2016; Age: 50~80 years old; ? Gender is not limited; ? Dominant stroke events occurred, and the course of disease was 0-3 months before enrollment; (5) The MMSE score was 16-26 points, and the MoCA score was 19-25 points; ? Clear mind, generally good condition, can cooperate with examination and treatment; ? Patients were enrolled voluntarily and signed the treatment consent
Exclusion criteria
Exclusion criteria: ? There is no correlation between cognitive function impairment and brain function impairment. There was no history of stroke or Transient ischemic attack (TIA) before the onset of the disease. ? Complicated with serious damage to other organs; ? Patients who are unable to complete cognitive tests due to motor, sensory or language disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MMSE (mini mental status exam);MoCA(Montreal Cognitive Assessment);CDR (Clinical Dementia Rating);SDSD(Dementia syndrome classification scale);inflammatory factor;HMGB1;pSrc; | — |
Secondary
| Measure | Time frame |
|---|---|
| Security detection;Risk factors related indicators of cerebrovascular disease; | — |
Countries
China
Contacts
The Second Affiliated Hospital of Anhui University of Chinese Medicine