The cornea and ocular surface diseases
Conditions
Interventions
Sponsors
The second affiliated hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: (1) conform to the FS - LASIK surgery indications, diopter (D) not more than 10.00 spherical myopia, astigmatism is less than 5.00D, obvious refractive stability (spherical or cylindrical increase of less than 0.50D per year) in the last 2 years, intraocular pressure =21 mmHg. (2) Age of 18-45 years old, male or female. (3) During the treatment, patients could actively cooperate with routine surgical medication and probiotic therapy according to the course of treatment. (4) Informed consent was obtained from patients and their families. Note: The patients were included in this study if all the above four criteria were met
Exclusion criteria
Exclusion criteria: (1) conform to the absolute and relative contraindications to FS-LASIK, suffering from severe dry eyes, clear corneal scar, Angle, cornea expansion, rest after laser ablation substrate thickness < 250 µm, active ocular or systemic diseases, glaucoma or retinal disease, serious systemic illness, history of eye surgery, pregnancy or lactation." (2) patients with severe organ diseases. (3) the immune system defects. (4) patients allergic to the drugs used in this study. (5) patients with resistance to related research work and poor compliance. Note: conform to any of the above, are excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence and severity of dry eye; | — |
Secondary
| Measure | Time frame |
|---|---|
| Corneal healing degree;visual quality;Intestinal microbiota homeostasis;Eye surface microbial homeostasis; | — |
Countries
China
Contacts
Public ContactYifeng Yu
The second affiliated hospital of Nanchang University
Outcome results
None listed