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Research progress of lidocaine in different ways in reducing hemodynamic changes of Dual lumen tracheal intubation (DLT)

Research progress of lidocaine in different ways in reducing hemodynamic changes of Dual lumen tracheal intubation (DLT)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400085910
Enrollment
Unknown
Registered
2024-06-20
Start date
2024-06-25
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary nodules

Interventions

Control group (C):DLT intubation was performed
L1 group (airway surface anesthesia group):2% lidocaine 1.5 mg/kg, laryngeal anesthesia tube was used to anesthesia the glottic and subglottic endotracheal surface.
L2 group (single intravenous injection group):2% lidocaine 1.5 mg/kg lidocaine induction period single intravenous injection
L3 group (intravenous continuous pumping group):loading dose of 2% lidocaine was given by a single intravenous injection of 1.5 mg/kg lidocaine during the induction period, and then maintenance dose o

Sponsors

Sichuan Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1)Age: 18<= Age <=80 years old; (2) ASA I-II; (3) Thoracic surgery patients requiring DLT tracheal intubation; (4) BMI 18-30 kg/m2; (5) Have the ability to comply with the study protocol

Exclusion criteria

Exclusion criteria: (1)Patients with severe heart, lung, and kidney diseases; (2) Forced expiratory volume in the first second [FEV1] or forced vital capacity [FVC]30); (4) Have a history of cold or sore throat within 2 weeks; (5) People who have taken analgesics or used opioids within 7 days; (6) Patients with past intubation difficulties or expected intubation difficulties and possible repeat intubation; (7) The mental state can not cooperate, suffering from mental diseases, no self-control, can not express clearly.

Design outcomes

Primary

MeasureTime frame
Incidence of reactive hypertension induced by intubation during anesthesia induction;

Secondary

MeasureTime frame
Postoperative throat related complications;Postoperative pulmonary complications;

Countries

China

Contacts

Public ContactLi peng

Sichuan Provincial People's Hospital

lipengmazui@qq.com+86 136 6816 9590

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026