general anesthesia without intubation
Conditions
Interventions
R-E Group:Sedation/anesthesia was induced using remimazolam (0.15 mg/kg) in combination with etomidate (0.1 mg/kg). Additional remimazolam (2.5mg each) was added intermittently during maintenance.
R-P Group:Sedation/anesthesia was induced using remimazolam (0.15 mg/kg) in combination with propofol (0.75 mg/kg). Additional remimazolam (2.5mg each) was added intermittently during maintenance.
Sponsors
Qingdao Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) age >18 years, elective gastroenteroscopy under procedural sedation; (2) ASA I-III.
Exclusion criteria
Exclusion criteria: (1) Refusal to sign the informed consent form;(2) Severe respiratory depression;(3) Acute or severe bronchial asthma;(4) Known or suspected gastrointestinal obstruction;(5) Known hypersensitivity to the drugs and ingredients used in this study;(6) Severe hepatic, renal, or adrenal insufficiency;(7) Long-term use of opioids;(8) Long-term use of benzodiazepines;(9) Anticipated difficult airway;(10) Adrenocortical insufficiency.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| respiratory depression; | — |
Secondary
| Measure | Time frame |
|---|---|
| hypoxemia;airway intervention;Sedation/anesthesia success rate; | — |
Countries
China
Contacts
Public ContactShoushi Wang
Qingdao Central Hospital
Outcome results
None listed