open cardiac surgery under CPB
Conditions
Interventions
Simple general anesthesia group (group A):Ultrasound-guided Bilateral TTP blocks by injecting with 0.9% saline 20ml on each side
TTP (ropivacaine) combined with general anesthesia (group B):Ultrasound-guided Bilateral TTP blocks by injecting with 0.3% ropivacaine (weight < 75kg) or 0.5% ropivacaine (weight = 75kg) 20ml on each
TTP (DEX plus ropivacaine) combined with general anesthesia group (group C):Ultrasound-guided Bilateral TTP blocks by injecting with 0.3% ropivacaine (weight < 75kg) or 0.5% ropivacaine (weight = 75kg
Sponsors
Longyan First Affiliated Hospital of Fujian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Elective open cardiac surgery under cardiopulmonary bypass ,age 18 ~65 years old, ASA physical status of ?~? ,NYHA Functional Class ?~?.
Exclusion criteria
Exclusion criteria: BMI > 35kg/m^2, refuse to implement transversus thoracis muscle plane block, secondary surgery, allergy to nonsteroidal anti-inflammatory drugs (NSAIDs), local anesthetics and opioids, renal or hepatic failure, severe coagulation disorders, infection at the site of injection , inability to cooperate with VAS score.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum glucose;Cortisol;C-reactive protein; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS score;Length of stay in the ICU ;Incidence of PONV ;Time of mechanical ventilation postoperative;Pulmonary complications; | — |
Countries
China
Contacts
Public ContactHangxiang Fu
Longyan First Affiliated Hospital of Fujian Medical University
Outcome results
None listed