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A prospective study to evaluate the gut microbiome alteration after ketogenic diet in healthy individuals

A prospective study to evaluate the gut microbiome alteration after ketogenic diet in healthy individuals

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400085884
Enrollment
Unknown
Registered
2024-06-20
Start date
2024-06-24
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

ketogenic diet intervention group:two-week intervention of ketogenic diet

Sponsors

The Affliated Panyu Central Hospital of Guangzhou Medical School
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: (1) age between 18-35, healthy male or female. (2) willing to participate in this investigation. (3) compliance to the follow-up procedure of this investigation.

Exclusion criteria

Exclusion criteria: (1) antibiotic or anti-fungal medication use 30 days prior to enrollment. (2) probiotic use 2 weeks prior to enrollment. (3) medication use that may influence carbohydrate or lipid metabolism (i.e. insulin, glibenclamide, phentolamine, furosemide, phenytoin sodium, cortisone, et al.) 1 month prior to enrollment. (4) co-morbidities that may influence carbohydrate or lipid metabolism or gut microbiome (i.e. obesity, hypothyroidism, asthma, hypertension, diarrhea, IBD, IBS, gastroenterology surgery history, et al.). (5) smokers or alcohol users.

Design outcomes

Primary

MeasureTime frame
Fecal microbiome;blood keto bodies;

Secondary

MeasureTime frame
Fecal metabolome;

Countries

China

Contacts

Public ContactLiping Cui

The Affliated Panyu Central Hospital of Guangzhou Medical School

13570261141@163.com+86 20 3485 8239

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026