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Association between sedation with remimazolam during a postoperative ICU stay and postoperative delirium: a prospective cohort study

Association between sedation with remimazolam during a postoperative ICU stay and postoperative delirium: a prospective cohort study

Status
Active, not recruiting
Phases
Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400085877
Enrollment
Unknown
Registered
2024-06-20
Start date
2024-06-20
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Delirium

Interventions

Remimazolam group (Remimazolam was used for continuous sedation during ICU stay.):None
Control group (Patients who did not receive remimazolam were included in the control group):None

Sponsors

The First Affiliated Hospital of Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: Selection of admission to the cardiothoracic surgery ICU between June 1, 2024 and May 31, 2025 Patients who met the inclusion criteria after phase I surgery. 1) older than 18 years old; 2) transferred to our department after elective surgery; 3) Intravenous sedation was required after transfer.

Exclusion criteria

Exclusion criteria: Exclusion criteria: (i) Written informed consent was not obtained from the patient; (ii) Patients who underwent a second operation during the same hospitalization; (iii) Postoperative coma and seizures; (iv) Abstinence from alcohol; (v) Patients with evident disturbance of consciousness or abnormal cognitive function prior to the operation.

Design outcomes

Primary

MeasureTime frame
The onset of delirium occurred within 5 days postoperatively.;

Secondary

MeasureTime frame
Duration of delirium;subsyndromic delirium;

Countries

China

Contacts

Public ContactLin lin

The First Affiliated Hospital of Sun Yat-sen University

919189465@qq.com+86 159 7552 9760

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026