Polycystic Ovary Syndrome
Conditions
Interventions
blank group:Patients with normal ovarian function who receive IVF-ET have no other intervention plans except for IVF related ovulation promotion interventions.
Disease group:There are no other intervention plans for PCOS patients except for IVF related ovulation promotion interventions.
Acupuncture group:For PCOS patients, in addition to IVF related ovulation promoting interventions, an additional acupuncture intervention plan for calming the mind and tonifying the kidney should be a
False acupuncture group:For PCOS patients, in addition to IVF related ovulation promoting interventions, a sham acupuncture intervention plan should be added.
Sponsors
Teaching Hospital of Chengdu University of Traditional Chinese Medicine
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for disease groups (1) Meets PCOS diagnostic criteria; (2) Age: 20-40 years old; (3) Meets the indications for in vitro fertilization embryo transfer in accordance with the revised technical specifications, basic standards, and ethical principles related to human assisted reproductive technology and human sperm bank issued by the Ministry of Health; (4) Voluntarily participate in the trial, have regular follow-up visits, and sign an informed consent form. Inclusion criteria for blank groups (1) Excluding infertility caused by ovarian dysfunction; (2) Age: 20-40 years old; (3) Meets the indications for in vitro fertilization embryo transfer in accordance with the revised technical specifications, basic standards, and ethical principles related to human assisted reproductive technology and human sperm bank issued by the Ministry of Health; (4) Voluntarily participate in the trial, have regular follow-up visits, and sign an informed consent form.
Exclusion criteria
Exclusion criteria: (1) Abnormal reproductive function of spouse; (2) Individuals with unclear consciousness, inability to express subjective discomfort symptoms, and accompanying mental illness; (3) Allergic constitution or allergy to acupuncture and moxibustion; (4) Infertility caused by fallopian tubes, female uterus without pregnancy function, clear or severe organic lesions in reproductive organs, acute infections or sexually transmitted diseases in the reproductive and urinary systems, chromosomal abnormalities, immune infertility; (5) Progressive malignant tumors or other serious wasting diseases, prone to concurrent infections and bleeding; (6) Individuals with primary diseases such as cardiovascular, liver, kidney, digestive, and hematopoietic systems that cannot withstand pregnancy; (7) Having been exposed to radiation, toxins, drugs that cause deformities and are still in effect, or having bad habits such as alcohol and drug abuse; (8) Those who are currently participating in other clinical research projects. Note: Anyone who meets any of the above criteria will be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Egg retrieval count;Egg retrieval size;Oocyte grading;Fertility;Excellent embryo rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Peripheral blood T, FSH, LH, E2 hormones;Follicular fluid T, FSH, LH, E2 hormones;MiRNA320, PI3K, Akt, and mTOR mRNA expression in follicular fluid;Self rating Anxiety Scal;Self-rating Depression Scale;Hamilton1depression1scale;Pittsburgh Sleep Quality Index;Traditional Chinese Medicine Syndrome Scoring Table; | — |
Countries
China
Contacts
Public ContactYang Lijie
Teaching Hospital of Chengdu University of Traditional Chinese Medicine
Outcome results
None listed