Schizophrenia
Conditions
Interventions
Health Control:None
Sponsors
Beijing Anding Hospital affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
16 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. 16-45 years old, right-handed, with a minimum of 6 years of education, and a Wechsler's intelligence score of over 70. 2. First episode schizophrenia: Meets the diagnostic criteria for schizophrenia in the American Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-5); In the first episode of mental illness, with a course of less than 5 years, and no history of antipsychotic drug use. 3. Health control: matched with the age, gender, and education level of the patient group; No history of mental illness or family history. 4. The subjects and/or their guardians voluntarily sign an informed consent form and comply with the research protocol
Exclusion criteria
Exclusion criteria: Coarse lateral hearing abnormalities, previous major auditory system diseases; Women have a family planning plan during pregnancy or follow-up period; Serious neurological diseases (history of traumatic brain injury or infection, brain tumors, cerebrovascular diseases, epilepsy, etc.) or other physical diseases; Abnormalities with clinical significance in physical examination, laboratory indicators, electroencephalogram, and electrocardiogram; Have a history of alcohol and drug abuse or dependence within 6 months; Received electroconvulsive therapy or direct current/transcranial magnetic stimulation therapy within 6 months; High risk of suicide or impulsive behavior; Unable or unwilling to cooperate with effective evaluation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prepulse inhibition; | — |
Secondary
| Measure | Time frame |
|---|---|
| DNA methylation;Immune inflammation proteins; | — |
Countries
China
Contacts
Public ContactMao Zhen
Beijing Anding Hospital affiliated to Capital Medical University
Outcome results
None listed