Chronic constipation
Conditions
Interventions
Experimental group:Chang lekang
Control group:Placebo
Sponsors
The Second Affiliated Hospital of Nanchang University
Eligibility
Sex/Gender
All
Age
45 Years to 100 Years
Inclusion criteria
Inclusion criteria: ? All subjects met the diagnostic criteria for Roman ? functional constipation; ? Age of subjects = 45 years old; ? All subjects are willing to provide written informed consent and follow the study procedures.
Exclusion criteria
Exclusion criteria: ? Subjects with past or current diseases such as intestinal obstruction, tumors, ulcers that may lead to secondary constipation of the digestive tract; ? Subjects with a history of gastrointestinal surgery; ? Subjects with serious diseases, such as serious cardiovascular, liver and kidney diseases; ? Subjects allergic to probiotics; ? Subjects who took antibiotics, probiotics, and other drugs that affected the evaluation of efficacy during the first three weeks of enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Average weekly number of spontaneous complete bowel movements ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bristol stool Typing Scale;Quality of Life Scale for constipation patients;Wexner Constipation Scoring Scale;High-throughput sequencing of intestinal flora; | — |
Countries
China
Contacts
Public ContactTu Huaijun
The Second Affiliated Hospital of Nanchang University
Outcome results
None listed