apnoeic oxygenation
Conditions
Interventions
Experimental group 2:Medium-flow nasal mask group 6 L/min
Control group 1:Nasal cannula 6 L/min
Control group 2:High-Flow Nasal Oxygenation 60 L/min
Experimental group 1:Low-flow nasal mask group 3 L/min
Experimental group 3:High-flow nasal mask group12 L/min
Sponsors
Gansu Provincial People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18-65 years 2. ASA grade I-II,BMI<30kg/m2 3. Elective surgery patients undergoing general anesthesia 4. Patients voluntarily participate in this study and sign the informed consent form
Exclusion criteria
Exclusion criteria: 1. Severe cardiopulmonary disease (NYHA III/IV; oxygenation index < 300, partial pressure of oxygen <60mmHg), peripheral vascular disease 2. Patients undergoing maxillofacial surgery 3. Nasal congestion, nasal lesions 4. Anticipated difficult airway 5. Pregnant women, moderate to severe anemia (Hb<90 g/L) 6. Patients at high risk of aspiration (e.g., intestinal obstruction, etc.) 7. Patients who cannot tolerate hypercapnia (pulmonary hypertension, neuromass lesions) 8. Patients with antral tumors
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| apnoeic time; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamics:mean arterial pressure (MAP);hemodynamic abnormalities during the test; new-onset arrhythmias; laryngospasm;gastric insufflation (cross-sectional area of gastric sinus under ultrasound);Postoperative complications: nausea and vomiting; discomfort or pain in the throat; dryness, itching and pain in the nasal passages.;Oxygen concentration under the sound gate;partial pressure of arterial oxygen,arterial carbon dioxide partial pressure,PH; | — |
Countries
China
Contacts
Public ContactWenjun YAN
Gansu Provincial People's Hospital
Outcome results
None listed