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Application of percutaneous acupoint electrical stimulation combined with esketamine in early anxiety and depression in patients with wound repair

Application of percutaneous acupoint electrical stimulation combined with esketamine in early anxiety and depression in patients with wound repair

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400085836
Enrollment
Unknown
Registered
2024-06-19
Start date
2023-12-25
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burns, ulcers, wound repair

Interventions

group TE:Percutaneous acupoint electrical stimulator was used to stimulate Baihui, Shenting, Yintang, Ershen point and other acupoints 30min before surgery, and continued to stimulate until the end of
group T:The percutaneous acupoint electrical stimulator stimulated Baihui, Shenting, Yintang, Ershen point and other acupoints until the end of the operation.
group E:Esketamine (0.4mg/kg) was injected intravenously before induction, followed by continuous pumping at 0.4mg/kg/h for 40min and then stopped.
group C:Conventional anesthesia, without acupoint electrical stimulation and esketamine intervention.

Sponsors

First Affiliated Hospital of Guangxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients receiving wound repair (burn wound, various ulcer wounds and various surgical wounds with poor healing) under general anesthesia 2. ASA grade I-III, 18-65 years old 3. The patient is conscious and the vital signs are relatively stable

Exclusion criteria

Exclusion criteria: 1. Refuse to participate in the research or quit the researcher for various reasons 2. Patients with head and face burns, shock, inhalation injuries, severe burns with more repeated combined injuries, and extremely severe burns 3. Patients with anxiety and depression scores >7 on the preoperative Hospital Anxiety Depression Scale (HADS) 4, preoperative Athens Insomnia Scale (AIS) score >4 points 5, perioperative severe hepatic and renal insufficiency, serious underlying diseases or systemic inflammatory diseases 6, have neurological and psychiatric diseases or take related drugs 7, cognitive dysfunction or inability to communicate 8, there are contraindications to the use of esketamine 9, TEAS contraindications, such as skin allergies, infections, itching, or wearing a pacemaker 10. Major organ damage or rescue occurred during perioperative period, and the patient was admitted to the intensive care unit (ICU) after surgery.

Design outcomes

Primary

MeasureTime frame
Postoperative anxiety and depression;

Secondary

MeasureTime frame
Postoperative sleep status;Postoperative recovery status;Postoperative pain level;

Countries

China

Contacts

Public ContactZhong Yu

First Affiliated Hospital of Guangxi Medical University

zzlugl@163.com+86 151 7792 9679

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026