hypercholesterolemia
Conditions
Interventions
Probucol in combination with statin (Moderate intensity atorvastatin, rosuvastatin, or other statins, etc):None
Sponsors
Fujian Provincial Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Patients aged =18 years and clinically diagnosed with hypercholesterolemia with high risk or above; (2) Willing to accept secondary prophylaxis: probucol combined with statins; (3) Sign informed consent.
Exclusion criteria
Exclusion criteria: Any patient who meets any of the following criteria will not be enrolled: (1) Complicated with severe heart, liver, and renal insufficiency, hematological diseases, and malignant tumors (assessed by the investigator); (2) Unwilling to attend or unable to cooperate with the accompanying visitors; (3) Patients who are pregnant, breastfeeding or have pregnancy plans and may be pregnant; (4) Allergic patients with statin and probucol tablets; Patients who have had serious adverse reactions to statin or probucol tablets in the past; (5) Patients with prolonged Q-T interval; Taking medications that prolong the Q-T interval; (6) Other situations that the researcher considers unsuitable for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Changes in blood lipids (focus on LDL-C, TC);LDL-C compliance rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| New major adverse vascular events;All-cause death rate;tumble rate;readmission rate; | — |
Countries
China
Contacts
Public ContactZheng Zheng
Fujian Provincial Hospital
Outcome results
None listed