IBS-C
Conditions
Interventions
experimental group:transcutaneous auricular vagus nerve stimulation (taVNS)
Sponsors
Department of Gastroenterology, The First Affiliated Hospital of USTC Anhui Provincial Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Patients who meet the diagnostic criteria for IBS-C; 2. Aged 18-65 years, regardless of gender; 3. Voluntarily accept treatment with this drug and sign an informed consent form, which complies with the relevant provisions of GCP.
Exclusion criteria
Exclusion criteria: 1. Patients with serious primary diseases such as cardiovascular, cerebrovascular, liver, kidney, and hematopoietic system diseases, hyperthyroidism, diabetes, or serious diseases (such as tumors) that affect their survival and mental patients; 2. Pregnant or preparing pregnant or lactating women; 3. Suspected or with a history of alcohol or drug abuse; 4. Individuals with cognitive impairment who cannot receive sufficient informed consent; 5. Patients who have participated in other clinical trials within the past month; 6. Patients who have undergone abdominal surgery within 6 months; 7. Individuals with general or special contraindications to physical therapy provided; 8. Researchers believe that there are patients with unsuitable factors for inclusion; 9. Patients who have been using various antibiotics and probiotics in the past month.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| IBS symptom score;IBS-Visual Analogue Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| anorectal manometry;autonomic nervous system;Bristol Fecal Scale;Serum neurotransmitter levels;Fecal gut microbiota; | — |
Countries
China
Contacts
Public ContactYu Yue
Anhui Provincial Hospital
Outcome results
None listed