Tubal Ectopic Pregnancy
Conditions
Interventions
Single-Dose Methotrexate Therapy in Tubal Ectopic Pregnancy Successful group/ Failed group:None
Sponsors
Zhejiang Provincial Hospital of Chinese Medicine
Eligibility
Sex/Gender
Female
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: (1) Patients presenting with vaginal bleeding or pelvic pain during early pregnancy. (2) Serum ß-hCG values below 4500 IU/L. (3) Transvaginal ultrasound revealing tubal ectopic pregnancy, excluding intrauterine pregnancy. When no intrauterine or ectopic pregnancy is detected, a series of serum ß - hCG measurements are performed to determine ectopic pregnancy. (4) Patients with an unruptured mass and stable hemodynamics. (5) Patients opting for medical management with methotrexate will receive a single-dose intramuscular injection (50 mg/m2) and will be informed of precautions and closely monitored.
Exclusion criteria
Exclusion criteria: (1) Hemodynamically unstable patients. (2) Patients preferring surgical or expectant management. (3) Patients diagnosed with non-tubal pregnancy. (4) Absolute contraindications to methotrexate (MTX) treatment, including intrauterine pregnancy, immunodeficiency, anemia, leukopenia, thrombocytopenia, MTX allergy, renal or hepatic insufficiency, pulmonary disease, active peptic ulcer disease, simultaneous use of intrauterine devices, breastfeeding, or fetal cardiac activity.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| respond to single-dose methotrexate therapy (Whether to conversions to surgery or receive MTX treatment again in the end); | — |
Countries
China
Contacts
Public ContactHu Yunyun
Zhejiang Provincial Hospital of Chinese Medicine
Outcome results
None listed