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Effect and Safety of Six Character Formula on Postoperative Pulmonary Complications in elderly patients under general anesthesia: a randomized controlled trial

Effect and Safety of Six Character Formula on Postoperative Pulmonary Complications in elderly patients under general anesthesia: a randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400085811
Enrollment
Unknown
Registered
2024-06-19
Start date
2022-12-22
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Pulmonary Complications

Interventions

test group:Perioperative Respiratory Six-character Formula Training+Conventional Lung Protection Measures
Control group:Conventional Lung Protection Measures

Sponsors

Guangdong Hospital of traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1)Patients aged =60 years (2)Patients undergoing elective orthopedic surgery, gastrointestinal surgery, hepatobiliary pancreatic surgery, and thoracic surgery under general anesthesia with elective tracheal intubation; (3)ASA I-III (4)Operation time =2 hours; (5) Patients voluntarily participated and signed informed consent form; (6)Patients cooperate with that training and obtain complete result information

Exclusion criteria

Exclusion criteria: (1)Preoperative history of acute lung injury or acute respiratory distress syndrome in last 3 months; (2)History of intubation or mechanical ventilation within 60 days prior to surgery; (3)Chronic obstructive pulmonary disease (COPD),obstructive sleep apnea ,asthma, restrictive lung disease, preoperative major chest infection, e.g. pulmonary tuberculosis, chest deformities such as pectus carinatum, pectus excavatum, thoracolumbar scoliosis, diaphragmatic hernias diagnosed on history; (4)Patients who have long-term use of hormone therapy before surgery (=3 months); (5)Patients who may have reoperation within 7 days after surgery; (6)Critical illness, including severe hepatic dysfunction (eg, hepatic failure), chronic renal failure (glomerular filtration rate 30kg/m2 (8) Patients with cognitive or neurological defcits; (9)Emergency operation;

Design outcomes

Primary

MeasureTime frame
Incidence of pulmonary complications (PPCs) in the 7 days postoperative;

Secondary

MeasureTime frame
Incidence of pulmonary complications (PPCs) in the 30 days postoperative;the PPCs severity score within 7 days after surgery; Postoperative 30-day mortality;length of ICU stay postoperative;postoperative hospitalization;Incidence of pulmonary infection within 7 days postoperation;Incidence of atelectasis within 7 days postoperative;Incidence of hydrothorax within 7 days postoperative;Postoperative pulmonary function;Mechanical ventilation duration;Postoperative arterial oxygen saturation;Hospitalization fee;

Countries

China

Contacts

Public ContactGaofeng Zhao

Guangdong Hospital of traditional Chinese Medicine

zhaogaofeng_97@163.com+86 159 2038 7021

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026