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Effect of remazolam on emerge agitation in patients undergoing nasal surgery: a randomized controlled clinical study

Effect of remazolam on emerge agitation in patients undergoing nasal surgery: a randomized controlled clinical study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400085806
Enrollment
Unknown
Registered
2024-06-19
Start date
2024-06-25
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Emergence Agitation

Interventions

Remazolam group:Anesthesia was induced and maintained by intravenous remazolam
Propofol group:Anesthesia was induced and maintained by intravenous injection of propofol

Sponsors

Nanchong Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing nasal surgery under elective general anesthesia were of all genders and aged = 18 years 2. Body mass index 19-28kg /m2 3. ASA Grade I - III 4. All candidates agreed to participate in the study and signed

Exclusion criteria

Exclusion criteria: 1. Basic values: systolic pressure > 160mmHg or diastolic pressure > 100mmHg, heart rate 100bpm 2. Acute respiratory infections, acute episodes of COPD, poorly controlled asthma 3. Mental disorders include schizophrenia, depression, cognitive dysfunction and so on 4. Allergic to the investigational drug 5. Patients with a history of taking benzodiazepines in the last three months 6. Pregnant and lactating women 7. Severe complications (including but not limited to renal insufficiency, liver insufficiency, cerebrovascular accident, heart failure, myocardial infarction, etc.)

Design outcomes

Primary

MeasureTime frame
Emergence Agitation;

Secondary

MeasureTime frame
Adverse reaction;

Countries

China

Contacts

Public ContactLi Linji

Nanchong Central Hospital

llj-stephen@163.com+86 155 8300 9555

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026