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Comparative observation of the effects of different concentrations of atropine on myopia control and tear film in adolescents: a multicenter, prospective, non randomized controlled trial

Comparative observation of the effects of different concentrations of atropine on myopia control and tear film in adolescents: a multicenter, prospective, non randomized controlled trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400085795
Enrollment
Unknown
Registered
2024-06-18
Start date
2023-06-04
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

myopia

Interventions

0.01% Research Group:0.01% atropine eye drops
0.025% Research Group:0.025% atropine eye drops
0.05% Research Group:0.05% atropine eye drops

Sponsors

Inner Mongolia Chaoju Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 14 Years

Inclusion criteria

Inclusion criteria: (1) Age: 6-14 years old (2) Myopic patients with astigmatism less than or equal to -2.50 D; (3) The best corrected visual acuity (BSCVA) is 20/25 or higher; (4) Have not worn corneal shaping glasses; (5) Patients who wear single focus frame glasses to correct their vision and are willing to undergo the experiment.

Exclusion criteria

Exclusion criteria: (1) Previous cataract, glaucoma, trauma and other eye diseases, diabetes; (2) The intraocular pressure is higher than 21 mmHg; (3) Received atropine mydriasis within 3 months; (4) A known history of atropine allergy.

Design outcomes

Primary

MeasureTime frame
Uncorrected Distance Visual Acuity (UCVA);Best Corrected Visual Acuity (BCVA);Corneal thickness;Intraocular pressure (IOP);Eye axis length (AL);

Secondary

MeasureTime frame
Ocular position;Tear Meniscus Height (TMH);Tear Film Break Up Time (BUT);Lacrimal film distribution;Tear film thickness;Meibomian gland analysis;Questionnaire information;

Countries

China

Contacts

Public ContactHuixia Li

Inner Mongolia Chaoju Eye Hospital

574780042@qq.com+86 133 0471 0678

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026