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Propensity score-matching analysis of retrograde artery first approach pancreatosplenectomy versus radical antegrade modular pancreatosplenectomy for ‘shoulder’ pancreatic cancers: retrospective cohort study

Propensity score-matching analysis of retrograde artery first approach pancreatosplenectomy versus radical antegrade modular pancreatosplenectomy for ‘shoulder’ pancreatic cancers: retrospective cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2400085782
Enrollment
Unknown
Registered
2024-06-18
Start date
2024-06-19
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pancreatic cancer

Interventions

RAFAPS group (Retrograde artery first approach pancreatosplenectomy (RAFAPS). Actually it's not called intervention because it was a observational retrospective study, so I described it as observation
RAMPS group (Radical antegrade modular pancreatosplenectomy (RAMPS) . This is control group.):None

Sponsors

National High Level Hospital Clinical Research Funding (2022-PUMCH-B-004 & 2022-PUMCH-D-001), CAMS Innovation Fund for Medical Sciences (2021-I2M-1-002 & 2022-I2M-C&T-B-030).
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria were as follows: 1. Male or female patients aged from 18-80 years. 2. Adhere to surgical indications and planned for laparoscopic or robotic pancreatosplenectomy.(Resectable pancreatic malignant tumours, tumours located in the shoulder area of the pancreas). 3. With a ASA classification from I-III.

Exclusion criteria

Exclusion criteria: The exclusion criteria were as follows: 1. History of major upper abdominal surgery (such as pancreatectomy, gastrectomy, hepatectomy or splenectomy), except choleceystectomy. 2. Pancreatic head benign or malignant tumours. 3. Benign distal pancreatic tumors, or distal pancreatic malignant tumor with boundary far from the line connecting the celiac trunk and SMA 4. History of radiation therapy for abdominal or pelvic lesions. 5. Pancreatic injury. 6. Severe cardiopulmonary dysfunction.

Design outcomes

Primary

MeasureTime frame
Negative retroperitoneal margin rate;

Secondary

MeasureTime frame
Estimated blood loss ;Operative time;Postoperative pancreatic fistula;Delayed gastric emptying;

Countries

China

Contacts

Public ContactFeng Tian

Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College

tianfeng@pumch.cn+86 151 0104 1029

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026