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Sufentanil pretreatment combined with BIS guided target controlled infusion of propofol in Gynecological general anesthesia

Sufentanil pretreatment combined with BIS guided target controlled infusion of propofol in Gynecological general anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400085772
Enrollment
Unknown
Registered
2024-06-18
Start date
2024-07-01
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gynecological general anesthesia

Interventions

pretreatment group:At the beginning of anesthesia induction, sufentanil 0.3 ug/kg was given slowly intravenously for 30 seconds
control group:At the beginning of anesthesia induction, equal amount of physiological saline was given slowly intravenously for 30 seconds

Sponsors

Beijing Obstetrics and Gynecology Hospital, Capital Medical University/ Beijing Maternal and Child Health Care Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: ? Age: 20 ~ 60 years old; ? BMI: 16.5 ~ 28kg/m2; ? ASA I ~ II. Adult female patients who plan to undergo elective gynecological laparoscopic surgery in Beijing Obstetrics and Gynecology Hospital, Capital Medical University, be visited and evaluated by an anesthesiologist before surgery and admitted.

Exclusion criteria

Exclusion criteria: ? Have a history of chronic pain or use of any sedatives or analgesics; ? Patients who are allergic to any of the drugs involved in this study.

Design outcomes

Primary

MeasureTime frame
Propofol dosage required to reduce BIS to 50;

Secondary

MeasureTime frame
Time taken for BIS to decrease to 50;Total propofol dosage during anesthesia induction;Total time of anesthesia induction;The lowest BIS value during anesthesia induction;Changes in hemodynamic indicators during anesthesia induction period;Application of vasoactive drugs during anesthesia induction period;Propofol injection pain;Other adverse reactions;

Countries

China

Contacts

Public ContactZhu Teng

Beijing Obstetrics and Gynecology Hospital, Capital Medical University/ Beijing Maternal and Child Health Care Hospital

mzkzhuteng@163.com+86 155 1049 3608

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026