Helicobacter pylori infection
Conditions
Interventions
Treatment group:Amoxicillin 1g 3 times a day and Vonoprazan 20mg 2 times a day
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
5 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Agree to 13C Helicobacter pylori urea breath test (13C-UBT); 2. the patients with 13C-UBT positive test agree to receive eradication treatment and gastroscopy; 3. Sign the informed consent form, agreeing to provide the remaining blood samples for clinical examination, take gastric mucosa tissue under gastroscope and provide basic clinical information.
Exclusion criteria
Exclusion criteria: 1. Those who have not received antiretroviral therapy; 2. Those who cannot cooperate with the improvement of gastroscopy after clinical evaluation; 3. Pregnant women or patients complicated with other serious diseases, such as heart failure, liver failure, renal failure or respiratory failure; 4. Have a history of allergic reaction to one or more drugs in the treatment plan; 5. Mental illness, poor treatment compliance, unable to cooperate with follow-up; 6. Previously received helicobacter pylori eradication treatment; 7. Taking antibiotics, bismuth or acid inhibitors within 4 weeks before detecting 13C-UBT; 8. Refusing to provide specimens or signing informed consent or relevant clinical information.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Helicobacter pylori eradication rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Compliance; | — |
Countries
China
Contacts
Public ContactHong Li
West China Hospital of Sichuan University
Outcome results
None listed