Gastric cancer
Conditions
Interventions
Experimental group:Traditional Chinese medicine And Standard treatment
Control group:placebo And Standard treatment
Sponsors
Wangjing Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: ? Age 18-75 years old, gender is not limited; ?The diagnostic criteria of advanced gastric adenocarcinoma, and simultaneously met (1), (2) and (3) : (1) Stage IV; (2) Negative HER-2 gene test; (3) Immunohistochemical results were pMMR (MLH1+,PMS2+,MSH2+ and MSH6+). ? Meet the diagnostic criteria of Qixue deficiency syndrome. ? No antitumor therapy has been given since the diagnosis of advanced gastric cancer; ?ECOG score 0-2 points; ? Expected survival =3 months; ? Volunteer to join the study, sign the informed consent, and comply with the follow-up;
Exclusion criteria
Exclusion criteria: ? Patients with primary tumors of other sites; ? Treating patients who are or will participate in other clinical trials requiring intervention; ? Patients with severe, uncontrolled organic disease or infection, such as decompensated heart, lung and renal failure, resulting in inability to tolerate chemotherapy; ?Patients with a known allergy or intolerance to the investigational drug; ? Patients with mental illness; ? Pregnant or lactating patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Overall Survival;progression-free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| Objective Response Rate;QLQ-STO22;PG-SGA; | — |
Countries
China
Contacts
Public ContactXue Peng
Wangjing Hospital, China Academy of Chinese Medical Sciences
Outcome results
None listed