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Clinical study of the effect of nicardipine atropine pretreatment on hemodynamic changes during the treatment of trigeminal neuralgia by percutaneous microballoon compression

Clinical study of the effect of nicardipine atropine pretreatment on hemodynamic changes during the treatment of trigeminal neuralgia by percutaneous microballoon compression

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400085752
Enrollment
Unknown
Registered
2024-06-18
Start date
2024-06-20
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Trigeminal cardiac reflex

Interventions

Group A:Atropine
Group C:Atropine combined with Nicardipine

Sponsors

Liaoning Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1, Patient age range from 18 to 80 years old (including boundary values); 2. Plan to select (Percutaneous compression of the trigeminal ganglion) PCTG to treat primary trigeminal neuralgia; 3, The patient has the American Society of Anesthesiologists (ASA) score I to II; 4, Cardiopulmonary function is normal; 5, Voluntarily sign the informed consent;

Exclusion criteria

Exclusion criteria: 1. Bradycardia (HR<50 bpm) and arrhythmia in the past; 2. Mental or nervous system diseases; 3. Severe heart, lung, brain or kidney disease; 4. Patients with intracranial hemorrhage who are estimated to have not completely stopped bleeding; 5. Intracranial hypertension patients in acute stage of cerebral stroke; 6. Patients with a history of allergy to the experimental drug; 7. Pregnant and lactating women; 8. Illiterate, language difficult to communicate patients, uncooperative patients;

Design outcomes

Primary

MeasureTime frame
Heart rate;

Secondary

MeasureTime frame
Systolic blood pressure;Diastolic blood pressure;Bispectral index;

Countries

China

Contacts

Public ContactWang Changming

Liaoning Provincial People's Hospital

TeamWangCM@163.com+86 177 0248 6100

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026