Chronic thromboembolic pulmonary hypertension
Conditions
Interventions
Intervention group:On the basis of routine treatment, add in hospital rehabilitation combined with home exercise rehabilitation treatment
control group:conventional therapy
Sponsors
Beijing Anzhen Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1) Age = 18 years old; 2) Diagnosed CTEPH; 3) Stable after PEA, BPA, and targeted therapy; 4) WHO functional classification II/III; 5) Sign written informed consent
Exclusion criteria
Exclusion criteria: 1) Other types of pH; 2) Fainting or malignant arrhythmia within 2 weeks; 3) Unable to undergo exercise rehabilitation training due to skeletal or muscle abnormalities; 4) Accompanied by persistent arrhythmia, severe chronic or acute liver, kidney or central nervous system diseases; 5) Expected inability to complete follow-up within 1 year after enrollment; 6) Refusal or inability to sign informed consent, or the researcher's judgment of other situations that may affect the progress of clinical research and the determination of research results.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 6-minute walking distance; | — |
Secondary
| Measure | Time frame |
|---|---|
| WHO functional classification;EmPHasis-10 pulmonary hypertension health quality of life score;Pulmonary hemodynamic evaluation indicators (mPAP, PVR, CO, CI, RAP, SvO2);Readmission due to worsening condition;All-cause death;Serious adverse events related to exercise; | — |
Countries
China
Contacts
Public ContactWan Jun
Beijing Anzhen Hospital Affiliated to Capital Medical University
Outcome results
None listed