Patients requiring general anesthesia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1, age > 18 one full year of life; 2 line, patients with general anesthesia, surgical duration > 60 min;
Exclusion criteria
Exclusion criteria: 1, patients allergic to narcotic drugs; 2, known difficult airway, and severe asthma patients; 3, calm analgesic drug use history (or test drug screening positive); 4, nervous system diseases, mental illness; 5. Pregnant patients; 6, refused to take part in the experiment of patients; 7. Severe cognitive impairment, hearing or visual impairment; 8, other drug studies are ongoing.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To investigate the correlation between the A/B/C/D/E/F six types of electroencephalogram (EEG) microstates and the incidence of neurological complications.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Eeg microstate report parameters: duration, frequency of occurrence, coverage, transition probability, global explained variance correlation with anesthesia emergence time, length of hospital stay, and postoperative mortality.;Transcranial color Doppler ultrasound cerebral blood flow parameters: time average velocity (TAP), peak systolic velocity (PSV), end diastolic velocity (EDV), pulsatility index (PI), resistance index (RI) and electroencephalogram microstate parameters correlation.;Cerebral oxygen saturation, peak frequency and eeg alpha state parameter correlation.; | — |
Countries
china
Contacts
the first affiliated hospital of nanchang university