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Effectiveness and safety of Fuzheng Buxue Recipe in Myelosuppression Induced by Platinum-based Chemotherapy Drugs: a quasi-experimental clinical trial

Research and Efficacy Evaluation on the Improvement of Myelosuppression Status in Cancer Patients after Chemotherapy by Fuzheng Buxue Recipe

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2400085703
Enrollment
Unknown
Registered
2024-06-17
Start date
2022-07-04
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chemotherapy-induced myelosuppresion

Interventions

Control group:Patients underwent platinum-based chemotherapy protocols or platinum-enhanced combination chemotherapy (with a 3-week cycle duration), complemented by standard oncology nursing care. Pre
FBR group:In addition to the standard treatment regimen for the control group, patients received FBR as a supplementary intervention. The FBR was meticulously prepared by the research team, adhering t

Sponsors

Nanjing Hospital of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
49 Years to 72 Years

Inclusion criteria

Inclusion criteria: ? Patients diagnosed with malignant tumors through clinical and laboratory examinations; ? Individuals aged between 18 and 85 years old with an expected survival period of =3 months; ? Patients with a Karnofsky Performance Status (KPS) scores =60 before chemotherapy; ? Patients scheduled to receive chemotherapy with platinum-based drugs, including oxaliplatin, cisplatin, carboplatin, nedaplatin, etc., or combination chemotherapy regimens based on platinum drugs; ? No history of food or drug allergies; ? Patients with ability to cooperate in completing survey questionnaires, provide regular follow-up data, and be followed up.

Exclusion criteria

Exclusion criteria: ? Special populations such as pregnant or lactating women, psychiatric patients; ? Halal or vegetarian individuals and those who personally object to consuming pig's trotters; ? Individuals with conditions such as gout, hyperlipidemia, or peptic ulcers, who should avoid purine-rich foods; ? Participants in other clinical trials.

Design outcomes

Primary

MeasureTime frame
blood parameters;adverse reactions;

Secondary

MeasureTime frame
TCM syndrome scores;KPS scores;

Countries

China

Contacts

Public ContactGuihua Xu

Nanjing University of Chinese Medicine

guihua.xu@njucm.edu.cn+86 153 6513 2927

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026