depression
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Samples must be stored at room temperature, centrifuged within 4 hours after collection, transferred to-60? within 10 hours, and then stored until testing; (2) The subject age is 12-18 years old, and the gender is not limited; (3) The subject and his legal guardian can communicate well with the investigator, understand and comply with the requirements of the study, participate voluntarily, and be willing to sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) The sample showed blood coagulation or hemolysis phenomenon; (2) Incorrect collection or storage of samples; (3) The subject is known to have other psychiatric disorders; (4) Patients with neurological diseases, brain trauma, cardiovascular and cerebrovascular diseases, severe liver and kidney function abnormalities, diabetes mellitus and other major physical diseases; (5) Receiving oral treatment or injection of hormone drug therapy in the latest week; (6) Patients with a history of surgery within the recent 3 months and hospitalization for more than 1 week; (7) Samples considered by the investigator to have other inappropriate factors to participate in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The coincidence rate of "inferred positive" and "positive" of ten diagnostic biomarkers for depression;Reference interval of serum concentration of various metabolites (liquid chromatography-tandem mass spectrometry) in Nanjing adolescents;Concentration of various metabolites and results of omics analysis in adolescent serum samples from Nanjing.; | — |
Countries
China
Contacts
Jiangsu Provincial Center for Disease Control and Prevention