tonsil or adenoids hypertrophy
Conditions
Interventions
Group R:infusion of remimazolam besylate
Group C:infusion of propofol
Sponsors
The Affiliated Women's and Children's Hospital of Ningbo University
Eligibility
Sex/Gender
All
Age
4 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1: 4-12 years old; 2: BMI 14-25 kg/m2; 3: ASA grade ?, II; 4: Undergoing Tonsillectomy or Adenoidectomy or both under general anaesthesia; 5: The guardian of the subject clearly understands and voluntarily participates in the study, and signs the informed consent form.
Exclusion criteria
Exclusion criteria: 1: History of neuropsychiatric diseases 2: History of cardiopulmonary diseases 3: Acute upper respiratory tract infection in the acute stage/recovery stage 4: History of any other chronic diseases 5: Pre-operative use of any sedative drugs 6: Preterm labour (gestation less than 36 weeks ) 7: Developmental delay 8: Any other condition for which remimazolam is not indicated and which, in the opinion of the investigator, makes participation in the study inappropriate (emergency surgery: hypovolemia, shock, or coma; combination of anaesthesia in addition to planned general anaesthesia; infectious cardiac disease; coagulation abnormalities, anaemia, or thrombocytopenia; hepatic or renal abnormalities; allergies or contraindications to esketamine, opioids, propofol, muscarinic medications, and their components; and patients who have been convicted of a crime or who have been subjected to a drug or drug abuse. (allergy or contraindication; have difficulty with respiratory management)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative sleep quality; | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence of postoperative delirium;recovery time; | — |
Countries
China
Contacts
Public ContactHu Qiong
The Affiliated Women's and Children's Hospital of Ningbo University
Outcome results
None listed