penile cancer
Conditions
Interventions
Gold Standard:Pathologic findings after lymph node dissection
Index test:18F-FDG and 18F-FAPI PET/CT imaging
Sponsors
The Third Xiangya Hospital of Central South University
Eligibility
Sex/Gender
Male
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Patients with biopsy or surgical pathologically confirmed squamous cell carcinoma of the penis. (2) Age: 18 to 75 years old. (3) Those who should undergo lymph node dissection according to the guidelines or require prophylactic lymph node dissection. (4) Voluntarily participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Claustrophobic or otherwise unable to complete the examination. (2) Alcoholic and drug-addicted patients, and those with mental disorders who are unable to cooperate. (3) Simultaneous combination of other malignant tumors. (4) Poor general condition that prevents completion of PET CT examination or inability to tolerate the procedure. (5) Poor compliance with psychiatric abnormalities or mental retardation and inability to cooperate with examination and treatment. (6) Other conditions that the clinical trial staff considers inappropriate for participation in this trial. (7) Those who refuse to undergo lymph node dissection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity, SE;Specificity, SP;Accuracy;Positive predicative value, PPV, PV+;Negative predictive value, NPV,PV-;Maximum Standardized Uptake Value, SUVmax;Mean Standardized Uptake Value, SUVmean; | — |
Secondary
| Measure | Time frame |
|---|---|
| Positive likelihood ratio;Negative likelihood ratio; | — |
Countries
China
Contacts
Public ContactMin Zhao
Department of Nuclear Medicine, The Third Xiangya Hospital of Central South University
Outcome results
None listed