The effect of preoperative substance abuse on postoperative delirium in patients undergoing major non-cardiac surgery: a prospective observational cohort study

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2400085584

Enrollment

Unknown

Registered

2024-06-12

Start date

2024-06-17

Completion date

Unknown

Last updated

2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative delirium

Interventions

Observation group:None

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Adults aged 18 years and above; Plan for elective major non-cardiac surgery (e.g., abdominal, thoracic, orthopaedic, or major urological surgery).

Exclusion criteria

Exclusion criteria: Dementia or history of serious mental illness (e.g., schizophrenia, epilepsy, etc.); Refuse to participate; Patients with severe liver and kidney dysfunction (child-pugh grade 3 and above; KIDGO diagnostic criteria to assess renal failure); Severe heart failure (NYHA grade ? or LVEF<30%); Emergency operation patients; Patients participating in other clinical studies; Unable to communicate or cooperate.

Design outcomes

Primary

Measure	Time frame
postoperative delirium;	—

Secondary

Measure	Time frame
Incidence of acute kidney injury(AKI);Postoperative pain level;Postoperative long-term cognitive dysfunction;Postoperative mortality;	—

Countries

China

Contacts

Public Contactzou haibin

Jiangxi Provincial People's Hospital (First Affiliated Hospital of Nanchang Medical College)

838991128@qq.com+86 177 7003 4217

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026