Ophthalmic Surgery
Conditions
Interventions
Propofol group:Propofol target-controlled infusion total intravenous anesthesia
Etomidate group:etomidate target-controlled infusion total intravenous anesthesia
Sponsors
Department of Anesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1) patients who voluntarily participated in the clinical study and obtained written informed consent; 2) patients who intended to undergo ophthalmic day surgery under general anaesthesia; 3) aged 65-80 years.
Exclusion criteria
Exclusion criteria: 1) BMI 28kg/m2; 2) history of psychiatric illness, cognitive dysfunction, history of alcoholism, or history of long-term psychotropic or chronic analgesic medication; 3) taking hormones or other immunosuppressants for =10 days within six months, or history of adrenocortical suppression or immune system disorders; 4) patients with hypothyroidism; 5) patients with a history of asthma ; 6) Allergy or other contraindications to the test drug; 7) Surgery within the last 3 months; 8) Participation in other studies within the last 30 days.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QoR15 scale;Proportion of patients with blood pressure/heart rate fluctuations > ± 20% of basal value; | — |
Secondary
| Measure | Time frame |
|---|---|
| VAS and PONV score; vas score;Pulmonary and cardiovascular complications;Time to respond to verbal commands and removal of the laryngeal mask; time to stay in the Post Anaesthetic Recovery Unit (PACU) and discharge from hospital; | — |
Countries
china
Contacts
Public ContactGuyan Wang
Department of Anesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing
Outcome results
None listed