lung disease
Conditions
Interventions
intervention group:rimazolam benzenesulfonate
control group:propofol
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
45 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1) 45 = age < 65 years old, regardless of gender. 2) elective thoracoscopic lung surgery (VAST). 3) the ASA score is I-III. 4) 18.5 kg/m2 < BMI < 28kg/m2. 5) voluntarily participate in the study and sign the informed consent form
Exclusion criteria
Exclusion criteria: 1) patients with severe heart, brain, liver and kidney diseases. 2) patients with mental disorders (schizophrenia, mania, bipolar disorders, insanity, etc.), long-term history of taking psychotropic drugs and cognitive impairment. 3) those who are allergic or contraindicated to benzodiazepines, opioids, propofol, muscle relaxants and their drug components. 4) patients who were judged to have difficulties in respiratory tract management (modified Mallampati score was grade IV). 5) participated in drug clinical trials as subjects in the past 3 months. 6) other situations in which the researchers think it is not appropriate to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of hypotension; | — |
Secondary
| Measure | Time frame |
|---|---|
| success rate of anesthesia induction;the duration of anesthesia induction;cough response during induction;cognitive impairment of delirium after surgery;postoperative in-hospital mortality; | — |
Countries
China
Contacts
Public ContactZhou Leng, Zhang Lu
West China Hospital of Sichuan University
Outcome results
None listed