autoimmune hepatitis
Conditions
Interventions
Gold Standard:Cirrhosis was determined based on histological findings from liver biopsy, clinical, biochemical, and/or radiological results.
Index test:Machine learning models (logistic regression model and extreme gradient boosting model), aspartate aminotransferase-to-platelet ratio index (APRI), and fibrosis-4 index (FIB-4).
Sponsors
the First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Retrospective collection of clinical and laboratory data from AIH patients aged =18 years, admitted to the hospital from 2016 to 2024, including demographic characteristics, serum biochemical indicators, routine blood tests, coagulation function tests, serum immunoglobulins, and serum autoantibodies.
Exclusion criteria
Exclusion criteria: Patients with comorbid conditions, such as other autoimmune liver diseases, viral hepatitis, drug-induced liver injury, non-alcoholic fatty liver disease (NAFLD) or alcoholic liver disease; those with liver cancer; or those who have undergone liver transplantation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accuracy;Sensitivity;Specificity;Positive predicative value;Negative predictive value; | — |
Countries
China
Contacts
Public ContactBingtian Dong
the First Affiliated Hospital of Anhui Medical University
Outcome results
None listed