disease of uterus
Conditions
Interventions
RL Group:Remifentanil 2 µg/L
The initial propofol effect chamber concentration during the anesthesia maintenance phase for the first patient in each group is 2 mg/L. The propofol concentration for each subsequent patient is deter
On the contrary, it will decrease by 0.5 mg/L.
RM Group:Remifentanil 4 µg/L
RH Group:Remifentanil 6 µg/L
Sponsors
The First Affiliated Hospital of USTC
Eligibility
Sex/Gender
Female
Age
30 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients undergoing gynecological laparoscopic hysterectomy under general anesthesia; American Society of Anesthesiologists (ASA) grade I-II; The age ranged from 30 to 65 years; Body mass index (BMI) : 18.5-29 kg/m2
Exclusion criteria
Exclusion criteria: poor compliance, unable to cooperate with the operation; with serious organic lesions (coronary heart disease, bronchial asthma, severe hypertension, severe blood system dysfunction, liver and kidney function, significant electrolyte abnormalities); II and above atrioventricular block, bradycardia (HR < 50 min/time), hypotension (SBP < 90mmHg); History of nervous system; A history of chronic pain; Drug addiction and alcohol abuse; A long history of opioid use; History of opioid allergy; patients with limited gastric emptying and gastroparesis; Patients with slow peristalsis and intestinal obstruction; those who participated in clinical trials of other drugs within the past 4 weeks; patients with other conditions considered by the investigator to be ineligible for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of awakening; | — |
Secondary
| Measure | Time frame |
|---|---|
| MAP;Heart rate;Duration of surgery;BIS;cerebral state index; | — |
Countries
China
Contacts
Public ContactHe keqiang
The First Affiliated Hospital of USTC
Outcome results
None listed