Heart failure with preserved ejection fraction in the type of qi deficiency and blood stasis
Conditions
Interventions
Control group:Standardized treatment + placebo pellets
Sponsors
Yueyang Hospital of Integrated Traditional Chinese Medicien and Western Medicine, Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
35 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) 35 years old = age = 85 years old, gender is not limited; (2) Stabilized for more than 1 month after volume management; (3) Outpatients or hospitalized patients who meet the diagnosis of heart failure with preserved ejection fraction; (4) Clinical diagnosis of Qi deficiency and blood stasis in Chinese medicine; (5) Those who voluntarily participate in the study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: (1) Patients with acute infarction, acute heart failure, cardiogenic shock, uncontrollable malignant arrhythmias, constrictive pericarditis, unrepaired valvular disease, complete atrioventricular block, pericardial tamponade, and obvious infections; (2) Patients with right heart failure, acute pulmonary edema, or acute hemodynamic disturbances due to pulmonary disease; (3) Patients with primary pulmonary hypertension, secondary severe pulmonary hypertension and combined chronic obstructive pulmonary disease; (4) Patients with severe uncontrolled hypertension (systolic blood pressure = 180 mmHg or diastolic blood pressure = 110 mmHg); (5) Patients with combined heart, liver, kidney, hematopoietic and metabolic systems and other serious primary diseases, malignant tumors, jaundice, liver and kidney insufficiency; (6) Women who are planning to become pregnant, pregnant or breastfeeding; (7) Patients who have participated or are participating in other clinical studies within 1 month prior to enrollment or who are allergic to Yi Xin prescription related traditional Chinese medicine.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cardiac function classification; | — |
Secondary
| Measure | Time frame |
|---|---|
| B-type natriuretic peptide precursor;Cardiac ultrasound;Growth-stimulated expression of gene 2 protein;Six-minute walk test;Traditional Chinese Medicine Syndrome Score Scale; | — |
Countries
China
Contacts
Public ContactFu Deyu
Yueyang Hospital of Integrated Traditional Chinese Medicine and Western Medicine, Shanghai University of Traditional Chinese Medicine
Outcome results
None listed