postoperative delirium
Conditions
Interventions
Sponsors
Chongqing Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: ?Age =65 years old; ? Planned elective operation with fragile hip fractures (femoral neck, femoral head, intertrochanteric or subtrochanteric fractures); ?American Society of Anesthesiologists (ASA) physical status I to IV
Exclusion criteria
Exclusion criteria: (1) Patients with chronic fractures, multiple trauma or fractures; (2) People with serious primary or secondary diseases, such as severe diseases of the liver, kidney and hematopoietic system, severe cardiopulmonary insufficiency or infectious diseases; (3) Prior to surgery, there was a clear history of neurological or psychiatric disorders or the use of corresponding medications; (4) A person who is addicted to drugs, alcohol or other substances; (5) Recent use of cholinergic and anticholinergic drugs and hormones; (6) Inflammation and a history of taking anti-inflammatory drugs; (7) Local skin rash, infection, lesions, ulcers, scars in the ear concha region; (8) Bradycardia (heart rate < 60 beats/min); (9) Patients with a history of implantable stimulators (such as pacemakers, implantable vagus nerve stimulators, deep brain stimulators, spinal cord electrical stimulators, etc.), cochlear implants, and metal implants in the body (except stomatology); (10) Communication problems, such as severe hearing or visual impairment; (11) Who refuse to participate or participate in another randomized clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative delirium; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of dNCR;AChE level in peripheral blood;Unplanned ICU admission rate;Length of stay, cost of stay;Incidence of postoperative complications;Postoperative mortality;BChE level in peripheral blood;TNF-a level in peripheral blood;IL-1ß level in peripheral blood;IL-6 level in peripheral blood;S-100ß level in peripheral blood; | — |
Countries
China
Contacts
Public ContactZhang liang
Chongqing Traditional Chinese Medicine Hospital
Outcome results
None listed